- September 24th, 2011
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Robert Hook the British scientist how discovered the smallest living organism called cells. The word cell comes from the Latin meaning cellular, meaning small room. Human body contain around 100tilan cells. These cells are divided into manly four sub cellular compartment:
1) Cell membrane
3) Cellular organelles
4) Genetic material.
In this website we explain about the role of the cytoskeleton in the mammalian cells. Mammalian cells have to arrange them self in the space and mechanically intact with the surrounding. They have to maintain their shape and coordinate the cellular compartments. Most of the cells are moving place to place. These cells have to coordinate complex mechanical functions like cell migration and cell division.All these mechanical properties of the cells depend on the amazing group of filaments called the cytoskeleton. Cytoskeleton is the scaffold on the top of the cells. Previously people thought that cytoskeleton unique to eukaryotes but resent studs show the presents of cytoskeleton in prokaryotes. Cytoskeleton involves different type of cellular factions. It helps to pull the chromosomes in the mitosis, give mechanical stability to the cells, helps in intracellular tricking, support the plasma membrane of the cells, and helps to contract the muscle cells.
Cytoskeleton is made up of three different types of protein Actin, Mictotubles and Intermediate filament . These proteins can exist in the cell in two forms monomer and polymer, monomer joined together forms filaments and form network. Depend on the external signaling this network can turn into monomers and vice versa. Intermediate filaments provide mechanical strength. Microtubles helps coordinate the dynamics of the intra cellular organ dynamics and helps intra cellular transport. Actin filament helps the dynamics of the cells and also maintained the shape of the cells.These microfilaments constantly interact with hundreds of other proteins in the cytoplasm.